Patient Experience

Patient Experience

Epik B5

A Phase III, randomized, double-blind, placebo-controlled study of alpelisib in combination with fulvestrant for men and postmenopausal women with HR-positive, HER2-negative advanced breast cancer with a PIK3CA mutation, who progressed on or after aromatase inhibitor and a CDK4/6 inhibitor
Description: This study will assess the efficacy of alpelisib plus fulvestrant in participants with Hormone receptor-positive, HER2-negative, advanced breast cancer after treatment with a CDK4/6 inhibitor and an aromatase inhibitor.
Study Phase: Phase 3
Principal Investigator: Dr Grainne O'Kane
Further information

Shamrock

Single arm phase 2 trial of neoadjuvant trastuzumab deruxtecan (T-DXd) with response-directed definitive therapy in early stage HER2-positive breast cancer: a cytotoxic chemotherapy-sparing approach to curative-intent treatment
Description: This trial will assess the effectiveness of trastuzumab deruxtecan (T-DXd) given in the neo-adjuvant setting (i.e before surgery) in women with HER2+ve breast cancer
Study Phase: Phase 3
Principal Investigator: Dr Ciara O'Hanlon Brown
Further information

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