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Coagulation tests are carried out for the investigation, diagnosis and monitoring of therapy in patients with bleeding and clotting disorders.

The coagulation laboratory provides a testing service for both inpatients and outpatients of St James’s Hospital and to general practitioners. It provides a tertiary referral laboratory service to other specified agencies within Ireland.

  • The Coagulation Laboratory service is comprised of the National Coagulation laboratory including the Haemostasis Molecular Diagnostic laboratory.

    The laboratory is the national referral laboratory for adult patients with bleeding and thrombotic disorders in Ireland. Laboratory testing includes both phenotypic and genotypic assessment of both heritable and acquired disorders of coagulation. There is a wide repertoire of tests available for the diagnosis and monitoring of patients with bleeding and thrombotic disorders. Laboratory testing for patients on anticoagulant therapy is performed in the Coagulation Laboratory.

    All samples received must be labelled correctly with the minimum number of patient identifiers as per laboratory policy. Samples received must be in the correct anticoagulant and received within the correct timeframe. For further information regarding sample requirements, please refer to the LabMed User Guide.

    Critical phone limits for Coagulation

  • There are laboratory testing guidelines and specific request forms for thrombophilia (including Lupus Anticoagulant) testing. Please see the Thrombophilia Testing Guidelines for more information.

    Evidence of informed patient consent is required for prothrombotic molecular testing (Factor V Leiden / Prothrombin gene mutation / APCR testing) this can be done via the Thrombophilia mutation analysis consent form.

     In addition, the Thrombophilia screen request form should be sent along with the samples for testing. All requests for thrombophilia testing are reviewed by the Coagulation Consultant Haematologist. Full clinical information and evidence of informed patient consent should be included on the request form. Requests where full clinical information or evidence of consent is not provided will be held in the laboratory pending receipt of same.

  • The HIT request form should be sent with samples for HIT testing.

    This request form includes the assessment of the pre-test probability score for HIT. The request form should be completed in full by the requesting clinician.

  • Refer to the LabMed User Guide for a complete list of available genetic tests and sample requirements. In addition, there is a specific HMD request form and HMD consent form that should be sent along with the samples for testing.

  • If frozen samples are being sent from the referral laboratory, sample aliquots must be stored in the appropriate sample vial. Please contact the laboratory for details of acceptable storage vials. Samples must remain frozen at all times; samples that are thawed on receipt will be unsuitable for testing. Frozen samples must be sent in the appropriate frozen container and remain in this frozen container for the duration of the transfer. They must not be removed and placed in a freezer in the courier van.

    The LabMed User Guide details all tests analysed, sample requirements, links to testing guidelines and specific request forms, turnaround times, availability, relevant notes and reference ranges for all coagulation tests.

  • Please refer to the Laboratory Policies and Guidelines for GPs and External Users for sample and request form acceptance criteria.

  • The laboratory is accredited to ISO 15189:2012 standard and is accredited with the Irish National Accreditation Board.

Contact Details

Monday to Friday, 8am to 8pm

How to find us

St James’s Centre for Laboratory Medicine and Molecular Pathology.