NMIC Bulletin Vol.30 No. 3 Use of medicines with anticholinergic activity

20 May, 2024

  • Many medicines that are commonly used in clinical practice are associated with anticholinergic activity
  • The use of medicines with high anticholinergic activity is associated with an increased risk of adverse clinical outcomes for patients, especially older patients
  • Anticholinergic scales can be used to identify medicines with anticholinergic activity and to assess the anticholinergic burden for an individual patient
  • The anticholinergic activity of a medicines should be considered when initiating medicines in older people, and the total anticholinergic burden assessed at medication review or if there are concerns regarding cognitive function