Professor Lowery returned to Ireland in 2017 having spent 8 years as a medical oncologist and translational researcher at Memorial Sloan Kettering Cancer Center following completion of an advanced fellowship in gastrointestinal oncology. 

Professor Lowery's clinical and translational research involves design and conduction of clinical trials in patients with gastrointestinal malignancies, incorporating translational study endpoints to validate predictive and prognostic biomarkers, identify mechanisms of resistance and guide the development of rational therapeutic strategies.

Her translational research interests use of real time genomic profiling to identify novel therapeutic strategies for gastrointestinal cancers, identification of non-coding alterations as modifiers of the DNA damage response pathway and generation of organoid models of cancer as a tool for precision oncology as a member of the PRECODE consortium. Her work is supported by the Pancreatic Cancer Research Fund (https://www.pcrf.org.uk), Science Foundation Ireland, through the Precision Oncology Ireland Consortium and the EU Horizon 2020 Marie Sklodowska-Curie Programme