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NMIC Bulletin Vol. 26 No. 3 Drug Interactions (1): General Principles

14 December, 2020

Drug Interactions (1): General Principles

  • Drugs interactions are an important cause of adverse drug reactions which can lead to an increased risk of morbidity and mortality
  • Increasing age and polypharmacy are major risk factors for drug interactions
  • The most clinically relevant drug interactions include those involving drugs with a narrow therapeutic index
  • The most important way to reduce the risk of patient harm is to recognise the potential for a drug interaction in an individual patient and to take appropriate action to avoid harm occurring