Gloriosa

Randomised multicentre, open-label, phase 3 of mirvetuximab soravtansine in combination with bevacizumab vs bevacizumab alone as maintenance therapy for patients with FRĪ±-high recurrent platinum-sensitive epithelial ovarian, fallopian tube, or primary peritoneal cancers who have not progressed after second-line platinum-based chemotherapy plus bevacizumab.
Description: This trial is for patients with platinum-sensitive epithelial ovarian, fallopian tube, or primary peritoneal cancers. The trial compares bevacizumab alone vs mirvetuximab soravtansine + bevacizumab
Study Phase: Phase 3
Principal Investigator: Prof Karen Cadoo
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NRG-GY019

A Randomized Phase III, Two-Arm Trial of Paclitaxel/Carboplatin/Maintenance Letrozole Versus Letrozole Monotherapy in Patients with Stage II-IV, Primary Low-Grade Serous Carcinoma of the Ovary or Peritoneum
Description: This trial assesses the effectiveness of 2 treatments ,Paclitaxel/Carboplatin/Maintenance Letrozole combination v's Letrozole Monotherapy in patients with Stage II-IV Primary Low-Grade Serous Carcinoma of the Ovary or Peritoneum.
Study Phase: Phase 3
Principal Investigator: Prof Karen Cadoo
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