Patient Experience
The primary goal of TSJCI’s Molecular and Precision Oncology Theme is to contribute vital molecular insights that facilitate a better understanding of cancer biology and may be translated into more refined diagnostics for cancer detection and new treatments for patients with cancer. This theme is also key to supporting the application of rational, disease and patient-focused approaches to cancer therapy.
Molecular Oncology research at TSJCI aims to identify and characterise the altered cellular processes that initiate and drive cancer. Our molecular oncology research is underpinned by inter-disciplinary and multi-disciplinary specialties that traverses boundaries between basic and translational research through to service delivery and the development and application of molecularly targeted therapies. Through identification of key molecular drivers and mechanisms of cancer development and progression using techniques including genomics/functional genomics, transcriptomics, proteomics, glycomics, metabolomics, computational biology, tumour imaging, in vitro and in vivo functional models, we aim to discover better cancer diagnostics and novel targets for therapeutic intervention.
Precision Oncology is an innovative approach to cancer treatment that ensures an individual patient’s treatment is specifically designed and targeted to their unique form of cancer. It’s the science of using each patient’s individual genomic profile – the genes that are mutated, causing their cancer to grow – to design a treatment protocol just for them, based on those genetic mutations that are driving their disease. The premise of this strategy is that molecular diagnostic testing is employed to triage patients and to select optimal therapies based on the genetic content of an individual patient’s tumour.
Our ultimate goal is to achieve ‘bench to beside’, feeding discoveries from basic and translational researchers into new cancer clinical trials for patients.
Theme Leads